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added a note about avoiding vial vacuums beacuse i guess that wasn't actually written anywhere

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2026-01-10 15:38:36 -08:00
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<head>
<meta content="text/html; charset=utf-8" http-equiv="content-type"/>
<title>A PRACTICAL GUIDE TO FEMINIZING HRT</title>
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<span class="ltx_personname"><a class="ltx_ref ltx_href" href="https://katea.gay/" title="">Katie Tightpussy</a>
</span></span>
</div>
<div class="ltx_dates">(December 31, 2025)</div>
<div class="ltx_dates">(January 10, 2026)</div>
<div class="ltx_abstract">
<h6 class="ltx_title ltx_title_abstract">DISCLAIMER</h6>
<p class="ltx_p">I am not a doctor. I do not work in medicine. I am not a medical professional in any capacity. I am a layperson offering lay opinions based on the extent of my own education and experiences. All information and assertions below should be treated accordingly as mere opinion rather than statement of fact or medical advice. This guide prioritizes community moral truth where scientific research falters. Basically, don’t get mad at me.</p>
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<div class="ltx_para" id="S5.SS25.p1">
<p class="ltx_p">Stable room temperature and away from light. High heat and UV can cause degradation of the carrier oil, whereas low temperatures can cause crystallization. Crystals can be dissolved and reincorporated, but it’s a potential cause for irritation if they aren’t fully dissolved. This goes for both sealed and unsealed vials.</p>
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<div class="ltx_para" id="S5.SS25.p2">
<p class="ltx_p">Additionally: before drawing from a vial, partially fill your syringe with air so that when you draw fluid from the vial you replace it with an equivalent volume of air. This simple step prevents a vacuum from forming over time inside the vial which can make drawing sigificantly more difficult.</p>
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</section>
<section class="ltx_subsection" id="S5.SS26">
<h3 class="ltx_title ltx_title_subsection">
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<p class="ltx_p"><span class="ltx_text ltx_font_italic">Dead space</span> refers to the amount of fluid that is wasted when performing an injection. This is fluid that is trapped in the syringe or in the needle. With a standard Luer lock needle/syringe this can be up to 0.1mL, whereas in an insulin needle can be as low as 0.003mL. Reducing dead space is recommended for economic reasons because it adds up to a lot of wasted estrogen. <a class="ltx_ref ltx_href" href="https://hrtcafe.net/Calc/" title="">This calculator</a> can be useful for estimating how much estrogen is wasted depending on the supplies used.</p>
</div>
<div class="ltx_para" id="S5.SS26.p2">
<p class="ltx_p">One thing to note if you are swapping needles for drawing and injecting, then you should pull the plunger back slightly prior to taking off the drawing needle so that the fluid inside the drawing needle is not wasted. It is very minor, but it can make a difference. <span class="ltx_text ltx_font_bold">Note as well that syringe markings already account for dead space, so you should not manually add more to your injection.</span> See Question <a class="ltx_ref" href="#S7.SS7" title="7.7 There was some air in my syringe. Will I die? ‣ 7 TROUBLESHOOTING ‣ A PRACTICAL GUIDE TO FEMINIZING HRT"><span class="ltx_text ltx_ref_tag">7.7</span></a> for another possible strategy if concerned about high dead space.</p>
<p class="ltx_p">One thing to note: if you are swapping needles for drawing and injecting, then you should pull the plunger back slightly prior to taking off the drawing needle so that the fluid inside the drawing needle is not wasted. It is very minor, but it can make a difference. <span class="ltx_text ltx_font_bold">Note as well that syringe markings already account for dead space, so you should not manually add more to your injection.</span> See Question <a class="ltx_ref" href="#S7.SS7" title="7.7 There was some air in my syringe. Will I die? ‣ 7 TROUBLESHOOTING ‣ A PRACTICAL GUIDE TO FEMINIZING HRT"><span class="ltx_text ltx_ref_tag">7.7</span></a> for another possible strategy if concerned about high dead space.</p>
</div>
</section>
<section class="ltx_subsection" id="S5.SS27">
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<p class="ltx_p"><a class="ltx_ref ltx_href" href="https://github.com/Juicysteak117/pghrt/" title="">Source code available here on GitHub.</a></p>
</div>
<div class="ltx_para ltx_noindent" id="Sx6.p2">
<p class="ltx_p">Full Compilation Datetime: <span class="undefined">Wed Dec 31 14:53:15 2025</span></p>
<p class="ltx_p">Full Compilation Datetime: <span class="undefined">Sat Jan 10 15:35:08 2026</span></p>
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<p class="ltx_p">(There aren’t LaTeXML bindings for <span class="ltx_text ltx_font_typewriter">datetime2</span>, <span class="ltx_text ltx_font_typewriter">hanging</span>, or <span class="ltx_text ltx_font_typewriter">hyphenat</span>, so the formatting is slightly ugly. If you’d really like to help me out, please write those bindings!!!)</p>
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<div class="ltx_para ltx_noindent" id="Sx6.p30">
<p class="ltx_p">2025-10-25: A variety of micro tweaks and the inclusion of Question <a class="ltx_ref" href="#S1.SS12" title="1.12 Is this chart accurate? ‣ 1 INTRODUCTION ‣ A PRACTICAL GUIDE TO FEMINIZING HRT"><span class="ltx_text ltx_ref_tag">1.12</span></a>. 20.2k words</p>
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<div class="ltx_para ltx_noindent" id="Sx6.p31">
<p class="ltx_p">2026-01-10: Added a clarification line under Question <a class="ltx_ref" href="#S5.SS25" title="5.25 How should I store a vial? ‣ 5 TECHNIQUE AND SUPPLIES ‣ A PRACTICAL GUIDE TO FEMINIZING HRT"><span class="ltx_text ltx_ref_tag">5.25</span></a> because that should be written somewhere. 20.3k words</p>
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