I am not a doctor. I do not work in medicine. I am not a medical professional in any capacity. I am a layperson offering lay opinions based on the extent of my own education and experiences. All information and assertions below should be treated accordingly as mere opinion rather than statement of fact or medical advice. This guide prioritizes community moral truth where scientific research falters. Basically, don’t get mad at me.
@@ -651,6 +651,9 @@Yes. Nothing is guaranteed, but many people experience substantial noticeable differences after swapping to injections even after years on HRT. These range from increased breast development, improved mental health, alleviated side effects of antiandrogens or other forms of estrogen, generally feeling better, etc. Switching is worth it.
It should be noted that time on HRT before injections is not ”wasted”, nor is there a limited window that estrogen is most effective for feminization. It is the consistency of injections that makes them as good as they are, but the destination will be largely the same either way. See Questions 11.5 and 11.6.
+If you are using Luer lock syringes, it is recommended to use a lower gauge than what you inject with so that it takes less time to draw from the vial. Too low can lead to coring (See Question 5.23), so at least 21-23G is recommended. If you have patience and lower volumes to inject, then higher gauges are recommended for the aforementioned coring risk reduction. Please note that the needle does not meaningfully blunt on the stopper. This question is irrelevant with insulin syringes because the needle is not removable.
+If you are using Luer lock syringes, it is recommended to use a lower gauge than what you inject with so that it takes less time to draw from the vial. Too low can lead to coring (See Question 5.23), so drawing with at least 21-23G is recommended. If you have patience and lower volumes to inject, then higher gauges are recommended for the aforementioned coring risk reduction. Please note that the needle does not meaningfully blunt on the stopper. This question is irrelevant with insulin syringes because the needle is not removable.
No. Because there is no “optimal” blood level for estrogen and because the therapeutic range of acceptable levels is so wide, body weight does not meaningfully affect dosage for HRT. It is for the same reason that slight deviations in dosage are unlikely to affect how you feel. There is no such thing as being “too light” or “too heavy” for HRT in any capacity.
+No. Because there is no “optimal” blood level for estrogen and because the therapeutic range of acceptable levels is so wide, body weight does not meaningfully affect dosage for HRT. It is for the same reason that slight deviations in dosage are unlikely to affect how you feel. There is no such thing as being “too light” or “too heavy” for HRT in any capacity.
Adjusting your dosage in increments of 0.1mg is a difference that should not be expected to be perceived simply because our bodies are not sensitive enough to such exact measurements, let alone the high possibility of imprecision when performing an injection that makes that certainty of this measurement unlikely. In other words, the accuracy of your dosage is more important than the precision.
+Adjusting your dosage in increments of 0.1mg is a difference that should not be expected to be perceived simply because our bodies are not sensitive enough to such exact measurements, let alone the high possibility of imprecision when performing an injection that makes that certainty of this measurement unlikely. In other words, the accuracy of your dosage is more important than the precision.
It isn’t! But it’s something I yell about because I think it’s good and I am tired of repeating myself because people keep asking and you’re reading this anyway, aren’t you? I love a captive audience. My standup routine is at the bottom.
+It isn’t! But it’s something I yell about because I think it’s good and I am tired of repeating myself because people keep asking and you’re reading this anyway, aren’t you? I love a captive audience. My standup routine is at the bottom.
Full Compilation Datetime: Fri Oct 17 00:32:11 2025
+Full Compilation Datetime: Sat Oct 18 18:22:21 2025
(There aren’t LaTeXML bindings for datetime2, hanging, or hyphenat, so the formatting is slightly ugly. If you’d really like to help me out, please write those bindings!!!)
@@ -2803,7 +2806,7 @@