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<head>
<meta content="text/html; charset=utf-8" http-equiv="content-type"/>
<title>A PRACTICAL GUIDE TO FEMINIZING HRT</title>
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<span class="ltx_personname"><a class="ltx_ref ltx_href" href="https://katea.gay/" title="">Katie Tightpussy</a>
</span></span>
</div>
<div class="ltx_dates">(October 21, 2025)</div>
<div class="ltx_dates">(October 24, 2025)</div>
<div class="ltx_abstract">
<h6 class="ltx_title ltx_title_abstract">DISCLAIMER</h6>
<p class="ltx_p">I am not a doctor. I do not work in medicine. I am not a medical professional in any capacity. I am a layperson offering lay opinions based on the extent of my own education and experiences. All information and assertions below should be treated accordingly as mere opinion rather than statement of fact or medical advice. This guide prioritizes community moral truth where scientific research falters. Basically, don’t get mad at me.</p>
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<h3 class="ltx_title ltx_title_subsection">
<span class="ltx_tag ltx_tag_subsection">6.7 </span>What types of injectable estrogen are DIY only?<a class="ltx_ref chain" href="#S6.SS7" onclick="copyURI(event)" title="Click to copy a link here"> 🔗</a></h3>
<div class="ltx_para" id="S6.SS7.p1">
<p class="ltx_p">Chiefly, <span class="ltx_text ltx_font_italic">estradiol enanthate</span>. Pharmaceutical sources will almost always prescribe you <span class="ltx_text ltx_font_italic">estradiol valerate</span>, but not always at a 40 mg/ml concentration. <span class="ltx_text ltx_font_italic">Estradiol cypionate</span> may occasionally be prescribed, but rarely above 5 mg/ml or 10 mg/ml concentrations, which are annoying to dose. The benefits provided by <span class="ltx_text ltx_font_italic">estradiol enanthate</span> alone are very good reasons to consider DIY, but you can get any ester at 40 mg/ml from DIY sources.</p>
<p class="ltx_p">Chiefly, <span class="ltx_text ltx_font_italic">estradiol enanthate</span> and <span class="ltx_text ltx_font_italic">estradiol undecylate</span>. Pharmaceutical sources will almost always prescribe you <span class="ltx_text ltx_font_italic">estradiol valerate</span>, but not always at a 40 mg/ml concentration. <span class="ltx_text ltx_font_italic">Estradiol cypionate</span> may occasionally be prescribed, but rarely above 5 mg/ml or 10 mg/ml concentrations, which are annoying to dose. The benefits provided by <span class="ltx_text ltx_font_italic">estradiol enanthate</span> alone are very good reasons to consider DIY, but you can get any ester at 40 mg/ml from DIY sources. <span class="ltx_text ltx_font_italic">Estradiol undecylate</span> is also DIY only for those inclined to self-experiment, though as noted I do not recommend it to the inexperienced.</p>
</div>
</section>
<section class="ltx_subsection" id="S6.SS8">
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<h3 class="ltx_title ltx_title_subsection">
<span class="ltx_tag ltx_tag_subsection">6.14 </span>Should I hold different DIY sources to different standards?<a class="ltx_ref chain" href="#S6.SS14" onclick="copyURI(event)" title="Click to copy a link here"> 🔗</a></h3>
<div class="ltx_para" id="S6.SS14.p1">
<p class="ltx_p">Likely, yes. Commercial brewers should also be held to a high standard if you are giving them money in exchange for product because they can afford to do it right. A mutual aid product on the other hand that is distributing vials for free might not be something that you can afford to be picky about, although that is not to say that the product is likely to be better or worse. As for a friend or yourself, only you can decide that!</p>
<p class="ltx_p">Likely, yes. Commercial brewers should be held to a high standard if you are giving them money in exchange for product because they can afford to do it right. A mutual aid product on the other hand that is distributing vials for free might not be something that you can afford to be picky about, although that is not to say that the product is likely to be better or worse. As for a friend or yourself, only you can decide that!</p>
</div>
</section>
<section class="ltx_subsection" id="S6.SSx3">
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<h3 class="ltx_title ltx_title_subsection">
<span class="ltx_tag ltx_tag_subsection">7.7 </span>There was some air in my syringe. Will I die?<a class="ltx_ref chain" href="#S7.SS7" onclick="copyURI(event)" title="Click to copy a link here"> 🔗</a></h3>
<div class="ltx_para" id="S7.SS7.p1">
<p class="ltx_p">No. While you obviously do not want to inject just air and it can affect dosage if there is too much in the syringe, a small amount of air under 0.1ml is almost certainly not going to cause issue for you. It might actually be recommended in some cases. For instance, the <span class="ltx_text ltx_font_italic">air lock technique</span> (a standard technique for injecting fluids that are irritating or can stain, not crucial knowledge for HRT) generally involves injecting 0.1-0.3ml of air, so you have nothing to be worried about. You aren’t doing intravenous injections.</p>
<p class="ltx_p">No. While you obviously do not want to inject just air and it can affect dosage if there is too much in the syringe, a small amount of air under 0.1ml is almost certainly not going to cause issue for you. It might actually be recommended in some cases. For instance, the <span class="ltx_text ltx_font_italic">air lock technique</span> (a standard technique for injecting fluids that are irritating or can stain; not crucial knowledge for HRT) generally involves injecting 0.1-0.3ml of air, so you have nothing to be worried about. You aren’t doing intravenous injections.</p>
</div>
</section>
<section class="ltx_subsection" id="S7.SS8">
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<h3 class="ltx_title ltx_title_subsection">
<span class="ltx_tag ltx_tag_subsection">8.13 </span>Can progesterone convert into <span class="ltx_text ltx_font_italic">dihydrotestosterone</span> (DHT)?<a class="ltx_ref chain" href="#S8.SS13" onclick="copyURI(event)" title="Click to copy a link here"> 🔗</a></h3>
<div class="ltx_para" id="S8.SS13.p1">
<p class="ltx_p">No. Well, strictly speaking yes, but also no. It is largely a myth, although <a class="ltx_ref ltx_href" href="https://whsah.co/posts/rethinking-progesterone-and-androgens/" title="">as outlined in detail by alix in this article</a>, for cases of people with <span class="ltx_text ltx_font_italic">nonclassical congenital adrenal hyperplasia</span> (ncCAH) progesterone can cause some negative side effects of increased androgenic activity. In those cases, discontinuing progesterone is recommended along with seeking out a formal diagnosis/treatment for potential adrenal disorders.</p>
<p class="ltx_p">No. Well, strictly speaking yes, but also no. It is largely a myth, although <a class="ltx_ref ltx_href" href="https://whsah.co/posts/rethinking-progesterone-and-androgens/" title="">as outlined in detail by alix (sic) in this article</a>, for cases of people with <span class="ltx_text ltx_font_italic">nonclassical congenital adrenal hyperplasia</span> (ncCAH) progesterone can cause some negative side effects of increased androgenic activity. In those cases, discontinuing progesterone is recommended along with seeking out a formal diagnosis/treatment for potential adrenal disorders.</p>
</div>
</section>
<section class="ltx_subsection" id="S8.SS14">
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<p class="ltx_p"><a class="ltx_ref ltx_href" href="https://github.com/Juicysteak117/pghrt/" title="">Source code available here on GitHub.</a></p>
</div>
<div class="ltx_para ltx_noindent" id="Sx6.p2">
<p class="ltx_p">Full Compilation Datetime: <span class="undefined">Tue Oct 21 14:38:18 2025</span></p>
<p class="ltx_p">Full Compilation Datetime: <span class="undefined">Fri Oct 24 00:40:33 2025</span></p>
</div>
<div class="ltx_para ltx_noindent" id="Sx6.p3">
<p class="ltx_p">(There aren’t LaTeXML bindings for <span class="ltx_text ltx_font_typewriter">datetime2</span>, <span class="ltx_text ltx_font_typewriter">hanging</span>, or <span class="ltx_text ltx_font_typewriter">hyphenat</span>, so the formatting is slightly ugly. If you’d really like to help me out, please write those bindings!!!)</p>
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