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okay yeah that's on me i guess for not clarifying. syringes already account for dead space. KISS!

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<head> <head>
<meta content="text/html; charset=utf-8" http-equiv="content-type"/> <meta content="text/html; charset=utf-8" http-equiv="content-type"/>
<title>A PRACTICAL GUIDE TO FEMINIZING HRT</title> <title>A PRACTICAL GUIDE TO FEMINIZING HRT</title>
<!--Generated on Tue Oct 21 13:10:20 2025 by LaTeXML (version 0.8.8) http://dlmf.nist.gov/LaTeXML/.--> <!--Generated on Tue Oct 21 14:38:18 2025 by LaTeXML (version 0.8.8) http://dlmf.nist.gov/LaTeXML/.-->
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<p class="ltx_p"><span class="ltx_text ltx_font_italic">Dead space</span> refers to the amount of fluid that is wasted when performing an injection. This is fluid that is trapped in the syringe or in the needle. With a standard Luer lock needle/syringe this can be up to 0.1mL, whereas in an insulin needle can be as low as 0.003mL. Reducing dead space is recommended for economic reasons because it adds up to a lot of wasted estrogen. <a class="ltx_ref ltx_href" href="https://hrtcafe.net/Calc/" title="">This calculator</a> can be useful for estimating how much estrogen is wasted depending on the supplies used.</p> <p class="ltx_p"><span class="ltx_text ltx_font_italic">Dead space</span> refers to the amount of fluid that is wasted when performing an injection. This is fluid that is trapped in the syringe or in the needle. With a standard Luer lock needle/syringe this can be up to 0.1mL, whereas in an insulin needle can be as low as 0.003mL. Reducing dead space is recommended for economic reasons because it adds up to a lot of wasted estrogen. <a class="ltx_ref ltx_href" href="https://hrtcafe.net/Calc/" title="">This calculator</a> can be useful for estimating how much estrogen is wasted depending on the supplies used.</p>
</div> </div>
<div class="ltx_para" id="S5.SS26.p2"> <div class="ltx_para" id="S5.SS26.p2">
<p class="ltx_p">One thing to note if you are swapping needles for drawing and injecting, then you should pull the plunger back slightly prior to taking off the drawing needle so that the fluid inside the drawing needle is not wasted. It is very minor, but it can make a difference. See Question <a class="ltx_ref" href="#S7.SS7" title="7.7 There was some air in my syringe. Will I die? ‣ 7 TROUBLESHOOTING ‣ A PRACTICAL GUIDE TO FEMINIZING HRT"><span class="ltx_text ltx_ref_tag">7.7</span></a> for another possible strategy if concerned about high dead space.</p> <p class="ltx_p">One thing to note if you are swapping needles for drawing and injecting, then you should pull the plunger back slightly prior to taking off the drawing needle so that the fluid inside the drawing needle is not wasted. It is very minor, but it can make a difference. <span class="ltx_text ltx_font_bold">Note as well that syringe markings already account for dead space, so you should not manually add more to your injection.</span> See Question <a class="ltx_ref" href="#S7.SS7" title="7.7 There was some air in my syringe. Will I die? ‣ 7 TROUBLESHOOTING ‣ A PRACTICAL GUIDE TO FEMINIZING HRT"><span class="ltx_text ltx_ref_tag">7.7</span></a> for another possible strategy if concerned about high dead space.</p>
</div> </div>
</section> </section>
<section class="ltx_subsection" id="S5.SS27"> <section class="ltx_subsection" id="S5.SS27">
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<p class="ltx_p"><a class="ltx_ref ltx_href" href="https://github.com/Juicysteak117/pghrt/" title="">Source code available here on GitHub.</a></p> <p class="ltx_p"><a class="ltx_ref ltx_href" href="https://github.com/Juicysteak117/pghrt/" title="">Source code available here on GitHub.</a></p>
</div> </div>
<div class="ltx_para ltx_noindent" id="Sx6.p2"> <div class="ltx_para ltx_noindent" id="Sx6.p2">
<p class="ltx_p">Full Compilation Datetime: <span class="undefined">Tue Oct 21 13:10:20 2025</span></p> <p class="ltx_p">Full Compilation Datetime: <span class="undefined">Tue Oct 21 14:38:18 2025</span></p>
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@@ -560,7 +560,7 @@ Stable room temperature and away from light. High heat and UV can cause degradat
\textit{Dead space} refers to the amount of fluid that is wasted when performing an injection. This is fluid that is trapped in the syringe or in the needle. With a standard Luer lock needle/syringe this can be up to 0.1mL, whereas in an insulin needle can be as low as 0.003mL. Reducing dead space is recommended for economic reasons because it adds up to a lot of wasted estrogen. \href{https://hrtcafe.net/Calc/}{This calculator} can be useful for estimating how much estrogen is wasted depending on the supplies used. \textit{Dead space} refers to the amount of fluid that is wasted when performing an injection. This is fluid that is trapped in the syringe or in the needle. With a standard Luer lock needle/syringe this can be up to 0.1mL, whereas in an insulin needle can be as low as 0.003mL. Reducing dead space is recommended for economic reasons because it adds up to a lot of wasted estrogen. \href{https://hrtcafe.net/Calc/}{This calculator} can be useful for estimating how much estrogen is wasted depending on the supplies used.
One thing to note if you are swapping needles for drawing and injecting, then you should pull the plunger back slightly prior to taking off the drawing needle so that the fluid inside the drawing needle is not wasted. It is very minor, but it can make a difference. See Question \ref{7-7} for another possible strategy if concerned about high dead space. One thing to note if you are swapping needles for drawing and injecting, then you should pull the plunger back slightly prior to taking off the drawing needle so that the fluid inside the drawing needle is not wasted. It is very minor, but it can make a difference. \textbf{Note as well that syringe markings already account for dead space, so you should not manually add more to your injection.} See Question \ref{7-7} for another possible strategy if concerned about high dead space.
\subsection{What do I do with my used syringes and needles?}\label{5-27} \subsection{What do I do with my used syringes and needles?}\label{5-27}